BDBM345432 1-(3,3-dimethylcyclopentyl)-4-[1-(4-isopropylphenyl)sulfonyl-4,5-dihydroimidazol-2-yl]piperazine::US10202354, Example 97

SMILES CC(C)c1ccc(cc1)S(=O)(=O)N1CCN=C1N1CCN(CC1)C1CCC(C)(C)C1

InChI Key InChIKey=MMHAOXQNDPJTLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345432   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 345432BDBM345432(1-(3,3-dimethylcyclopentyl)-4-[1-(4-isopropylpheny...)
Affinity DataIC50: 10.5nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent