BDBM347593 5-({3-[2-Methoxy-4-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)-N-methylpyridazin-3-amine::US9790201, 78

SMILES CNc1cc(cnn1)C(=O)N1CCCC(C1)c1ccc(cc1OC)C(F)(F)F

InChI Key InChIKey=BOBJLXWUZNOPBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347593   

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347593BDBM347593(5-({3-[2-Methoxy-4-(trifluoromethyl)phenyl]piperid...)
Affinity DataIC50: 3.00E+3nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent