BDBM35400 3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide::3-amino-N-[5-(propylthio)-1,3,4-thiadiazol-2-yl]-6-(2-thienyl)thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-[5-(propylthio)-1,3,4-thiadiazol-2-yl]-6-thien-2-ylthieno[2,3-b]pyridine-2-carboxamide::3-amino-N-[5-(propylthio)-1,3,4-thiadiazol-2-yl]-6-thiophen-2-yl-2-thieno[2,3-b]pyridinecarboxamide::3-azanyl-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carboxamide::MLS000085179::SMR000019719::cid_1773030

SMILES CCCSc1nnc(NC(=O)c2sc3nc(ccc3c2N)-c2cccs2)s1

InChI Key InChIKey=GMTLIJKJKRSHIP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 35400   

TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50:  1.24E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50:  2.57E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50:  2.57E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50:  4.45E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35400(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataIC50:  2.18E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay