BDBM355991 1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)-3-(2-chloro-7-(morpholin-2-yl)pyrazolo[1,5-a]pyrimidin-6-yl)urea::US10442808, Example 115::US9815842, Example 115

SMILES CC(C)(C)OC(=O)N1CCOC(C1)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12

InChI Key InChIKey=XNMBVECXAABCEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 355991   

LigandChemical structure of BindingDB Monomer ID 355991BDBM355991(US9815842, Example 115 | 1-(5-chloro-6-(2H-1,2,3-t...)
Affinity DataIC50: 0.0180nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 355991BDBM355991(US9815842, Example 115 | 1-(5-chloro-6-(2H-1,2,3-t...)
Affinity DataIC50: 0.0760nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 355991BDBM355991(US9815842, Example 115 | 1-(5-chloro-6-(2H-1,2,3-t...)
Affinity DataIC50: 0.0760nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details
US Patent