BDBM356569 N-(3-{7-[1-(1-Methyl-2-morpholin-4-yl-2-oxoethyl)-1H-pyrazol-4-yl]imidazo[1,2-b]pyridazin-3-yl}phenyl)-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 58::US10813930, Ex. No. 58

SMILES CC(N\C=C(/C=N)c1cnn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1)C(=O)N1CCOCC1

InChI Key InChIKey=ZDDSECBNTIOORK-IRLWCRFCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356569   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM356569(N-(3-{7-[1-(1-Methyl-2-morpholin-4-yl-2-oxoethyl)-...)
Affinity DataIC50: <10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM356569(N-(3-{7-[1-(1-Methyl-2-morpholin-4-yl-2-oxoethyl)-...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent