BDBM361577 (S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3- nitrophenyl)sulfonyl)-2-((1H-pyrrolo[2,3-b]pyridin- 5-yl)oxy)-4-(4-((6-(4-chlorophenyl)spiro[3.5]non-6- en-7-yl)methyl)piperazin-1-yl)benzamide::US10221174, Compound 6::US10829488, Compound 6::US11718613, Compound 6
SMILES [O-][N+](=O)c1cc(ccc1NC[C@H]1COCCO1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC3(CCC3)CC2)c2ccc(Cl)cc2)CC1
InChI Key
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 361577
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataIC50: 2nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
TargetBcl-2-like protein 11 [72-87](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataIC50: 2nMAssay Description:Bcl-2 and Bcl-xL Inhibition: Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respect...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataIC50: >5.00E+3nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
TargetBH3-interacting domain death agonist [79-99](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataIC50: >5.00E+3nMAssay Description:Bcl-2 and Bcl-xL Inhibition: Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respect...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataIC50: 2nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
TargetBcl-2-like protein 11 [81-106](Homo sapiens (Human))
The Regents Of The University Of Michigan
US Patent
The Regents Of The University Of Michigan
US Patent
Affinity DataIC50: 5.90nMAssay Description:Bcl-2 and Bcl-xL Inhibition: Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respect...More data for this Ligand-Target Pair