BDBM363010 3-((6-Chloro-7-fluoro-2-methyl-1-(2-(7-methyl-1,7-diazaspiro[3.5]nonan-1-yl)-2-oxoethyl)-1H-indol-3-yl)thio)benzoic acid ::US9850203, Compound 1-87

SMILES CN1CCC2(CCN2C(=O)Cn2c(C)c(Sc3cccc(c3)C(O)=O)c3ccc(Cl)c(F)c23)CC1

InChI Key InChIKey=KGZRJOSJYLUWNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363010   

TargetAutotaxin(Human)
Pharmakea

US Patent
LigandChemical structure of BindingDB Monomer ID 363010BDBM363010(US9850203, Compound 1-87 | 3-((6-Chloro-7-fluoro-2...)
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
US Patent