BDBM365163 4-(3-(3-chloro-4- fluorobenzyl)-3,4-dihydro-5- oxa-1,2,2a1- triazaacenaphthylen-7-yl)-N- (1-methyl-1H-pyrazol-5- yl)pyrimidin-2-amine::US10517878, Compound I-82::US10842799, I-82::US9867833, Compound I-82(S)
SMILES Cn1nccc1Nc1nccc(n1)-c1cc2OCC(Cc3ccc(F)c(Cl)c3)c3nnc(c1)n23
InChI Key InChIKey=JMXUHBKNIPMAEA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 365163
Affinity DataIC50: 12.4nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair