BDBM371562 4-chloro-5-((1-(2,6-difluorobenzyl)piperidin-3-yl)amino)-2-methylpyridazin-3(2H)-one::US10239861, Example 42

SMILES Cn1ncc(NC2CCCN(Cc3c(F)cccc3F)C2)c(Cl)c1=O

InChI Key InChIKey=JEJJCYAHCAGGCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371562   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandChemical structure of BindingDB Monomer ID 371562BDBM371562(4-chloro-5-((1-(2,6-difluorobenzyl)piperidin-3-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent