BDBM37549 5,6-dihydro-4H-1,3-thiazin-2-yl(o-tolyl)amine::MLS000098772::N-(2-methylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine::SMR000061099::cid_2384869

SMILES N#Cc1ccc(-c2ccc(C[C@H](NC(=O)c3ccc4[nH]ccc4c3Cl)C(=O)O)c3cccnc23)c(Cl)c1

InChI Key InChIKey=BUNDSUYBSCAHHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37549   

TargetIntegrin alpha-4/beta-7(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 37549BDBM37549(US11116760, Example 266)
Affinity DataEC50:  72.2nMAssay Description:The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent