BDBM37593 US11116760, Example 303

SMILES O=C(N[C@@H](Cc1ccc(-c2ncc3ccccc3c2Br)c2ncccc12)C(=O)O)c1c(Cl)cccc1Cl

InChI Key InChIKey=GBRDFKPTNVQRJH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37593   

TargetIntegrin alpha-4/beta-7(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 37593BDBM37593(US11116760, Example 303)
Affinity DataEC50:  9.40nMAssay Description:The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent