BDBM377607 N-(3,4-dihydro-2H-pyrrol-5-yl)-::US10266495, Compound I-19

SMILES Cc1cc2cc(CNc3cccc(c3)S(=O)(=O)NC3=NCCC3)c(=O)[nH]c2cc1C

InChI Key InChIKey=MOBJWBBPDOHGNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377607   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 377607BDBM377607(US10266495, Compound I-19 | N-(3,4-dihydro-2H-pyrr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent