BDBM390732 (R)-N-(3-Aminochroman-7-yl)-3-ethyl-4-methyl-1H-pyrazole-5-carboxamide::US9957261, Example 88

SMILES CCc1n[nH]c(C(=O)Nc2ccc3C[C@@H](N)COc3c2)c1C

InChI Key InChIKey=FJFPWZVOXCPDFX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390732   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 390732BDBM390732(US9957261, Example 88 | (R)-N-(3-Aminochroman-7-yl...)
Affinity DataKi:  8.30nMAssay Description:Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 390732BDBM390732(US9957261, Example 88 | (R)-N-(3-Aminochroman-7-yl...)
Affinity DataKi:  11.9nMAssay Description:Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent