BDBM394017 3-{4-[(trans-4- morpholin-4- ylcyclohexyl)amino] quinazolin-6-yl}-5- (trifluoromethyl)pyridin- 2-ol::US9969749, Example 2-5

SMILES Oc1ncc(C(F)(F)F)cc1-c1ccc2ncnc(N[C@H]3CC[C@H](N4CCOCC4)CC3)c2c1

InChI Key InChIKey=ODDOVURUHMIPIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394017   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 394017BDBM394017(US9969749, Example 2-5 | 3-{4-[(trans-4- morpholin...)
Affinity DataIC50: 928nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent