BDBM395572 2-(trans-4-((7- cyano-2-(3'-(3- (((R)-3-hydroxy- pyrrolidin-1-yl)- methyl)-1,7- naphthyridin-8- ylamino)-2,2'- dimethylbiphenyl-::US10308644, Example 184::US10800768, Example 184::US11339149, Example 184
SMILES Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CNC4CC[C@H](CC(O)=O)CC4)cc(C#N)c3o2)c1C
InChI Key InChIKey=JIAUMYWINJGMBT-XECYDNGLSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 395572
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent