BDBM396147 6-[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]methyl-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-amine::US10308667, Example 50

SMILES Cc1nc2nonc2c(N)c1Cc1ncc(c(Cl)n1)C(F)(F)F

InChI Key InChIKey=FYZYJKBBRCMZBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396147   

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 396147BDBM396147(6-[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]meth...)
Affinity DataIC50: 2.5nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent