BDBM399160 1-((3S,4R)-4-(3,4- difluorophenyl)-1-(2- methoxyethyl)pyrrolidin-3- yl)-3-(pyrazolo[1,5-a]pyridin- 3-yl)urea::US10323022, Example 637

SMILES COCCN1C[C@@H](NC(=O)Nc2cnn3ccccc23)[C@@H](C1)c1ccc(F)c(F)c1

InChI Key InChIKey=AXWBXJPREPKAPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 399160   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 399160BDBM399160(1-((3S,4R)-4-(3,4- difluorophenyl)-1-(2- methoxyet...)
Affinity DataIC50: 100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent