BDBM403490 US10335399, Example 4-1A::US10806724, Example 4-1A

SMILES CN(C[C@H]1CCc2c(O1)nc(cc2-c1ccc(F)cc1F)C(N)=O)CC(F)(F)F

InChI Key InChIKey=QCVOOLBKUHWWQR-LLVKDONJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403490   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403490(US10335399, Example 4-1A | US10806724, Example 4-1...)
Affinity DataIC50:  25nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403490(US10335399, Example 4-1A | US10806724, Example 4-1...)
Affinity DataIC50:  25nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent