BDBM408198 6-(1-(4-(5-Methylpyrimidin-2-yl)piperazin-1-yl)ethyl)quinoxaline::US10336775, Example 102::US11046712, No 102

SMILES CC(N1CCN(CC1)c1ncc(C)cn1)c1ccc2nccnc2c1

InChI Key InChIKey=NTGCJNRYROTQGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408198   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandChemical structure of BindingDB Monomer ID 408198BDBM408198(6-(1-(4-(5-Methylpyrimidin-2-yl)piperazin-1-yl)eth...)
Affinity DataIC50: 125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandChemical structure of BindingDB Monomer ID 408198BDBM408198(6-(1-(4-(5-Methylpyrimidin-2-yl)piperazin-1-yl)eth...)
Affinity DataIC50: 125nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent