BDBM411509 Methyl((6-((R)-3- methylmorpholino)-2- (1H-pyrrolo[2,3-b]- pyridin-4-yl)pyrimidin-4- yl)imino)(oxetan-3-yl)- lambda6-sulfanone::US10392376, Example 60::US10800769, Example 60
SMILES C[C@@H]1COCCN1c1cc(N=S(C)(=O)C2COC2)nc(n1)-c1ccnc2[nH]ccc12
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 411509
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 4nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand Info
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 41nMAssay Description:Inhibitors of ATR kinase are effective at inhibiting the ATR-driven phosphorylation of the downstream target Chk1 kinase at Serine 345, following the...More data for this Ligand-Target Pair
Ligand Info
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 4nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand Info