BDBM415551 (2R,3S,4R,5R)-2-((R)-hydroxy(1H-indol-7-yl)methyl)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diol (JJ-5)::US10428104, Example 82

SMILES Cc1ncnc2c1ccn2[C@@H]1O[C@H]([C@H](O)c2cccc3cc[nH]c23)[C@@H](O)[C@H]1O

InChI Key InChIKey=YTXRGQDFCUJCHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415551   

TargetProtein arginine N-methyltransferase 5(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 415551BDBM415551(US10428104, Example 82 | (2R,3S,4R,5R)-2-((R)-hydr...)
Affinity DataIC50: 150nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent