BDBM41765 4-[(6-hydroxy-2,4-diketo-1H-pyrimidine-5-carbonyl)amino]benzoic acid ethyl ester::4-[[(6-hydroxy-2,4-dioxo-1H-pyrimidin-5-yl)-oxomethyl]amino]benzoic acid ethyl ester::MLS000040367::SMR000058126::cid_662817::ethyl 4-[(6-hydroxy-2,4-dioxo-1H-pyrimidine-5-carbonyl)amino]benzoate::ethyl 4-[[6-oxidanyl-2,4-bis(oxidanylidene)-1H-pyrimidin-5-yl]carbonylamino]benzoate

SMILES CCOC(=O)c1ccc(NC(=O)c2c(O)[nH]c(=O)[nH]c2=O)cc1

InChI Key InChIKey=XWZUFKMEGYKBSH-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 41765   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM41765(4-[(6-hydroxy-2,4-diketo-1H-pyrimidine-5-carbonyl)...)
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM41765(4-[(6-hydroxy-2,4-diketo-1H-pyrimidine-5-carbonyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:List of compounds to be tested: 33 component starting materials and chemical analogs of the hits identified in the in vitro PLK1-PBD binding primary ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM41765(4-[(6-hydroxy-2,4-diketo-1H-pyrimidine-5-carbonyl)...)
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM41765(4-[(6-hydroxy-2,4-diketo-1H-pyrimidine-5-carbonyl)...)
Affinity DataIC50:  2.28E+3nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is More data for this Ligand-Target Pair
In DepthDetails PCBioAssay