BDBM423209 (R)-4-methyl-5-(4-((6- (4-methyl-1H-imidazol- 1-yl)pyridin-3-yl) methyl)piperazin-2-yl)iso- benzofuran-1(3H)-one::US10501449, Example 66-I

SMILES Cc1cn(cn1)-c1ccc(CN2CCN[C@@H](C2)c2ccc3C(=O)OCc3c2C)cn1

InChI Key InChIKey=GEBFWQPXZHENGW-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423209   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423209((R)-4-methyl-5-(4-((6- (4-methyl-1H-imidazol- 1-yl...)
Affinity DataIC50:  4.70nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent