BDBM42352 1-(5-(7-bromo-1H- benzo[d]imidazole-4- carbonyl)-2-(4-(2,2- difluorocyclobutyl)-2- hydroxyphenyl)- 2,3,4,5,5a,6,8,9- octahydro-7H-1,2,5,7- tetraazabenzo[cd]azulen- 7-yl)prop-2-en-1-one::US20250346600, Compound 6

SMILES C=CC(=O)N1CCc2nn(-c3ccc(C4CCC4(F)F)cc3O)c3c2C(C1)N(C(=O)c1ccc(Br)c2c1=NCN=2)CC3

InChI Key InChIKey=LBIUALFCXJVPNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42352   

LigandChemical structure of BindingDB Monomer ID 42352BDBM42352(1-(5-(7-bromo-1H- benzo[d]imidazole-4- carbonyl)-2...)
Affinity DataIC50: 3.25nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 42352BDBM42352(1-(5-(7-bromo-1H- benzo[d]imidazole-4- carbonyl)-2...)
Affinity DataIC50: 35nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details
US Patent