BDBM42423 4-(7-acryloyl-2-(4- cyclopropylphenyl)- 3,4,5,5a,6,7,8,9- octahydro-2H-1,2,5,7- tetraazabenzo[cd]azulene- 5-carbonyl)-1-(2,2,2- trifluoroethyl)pyridin- 2(1H)-one::US20250346600, Compound 68

SMILES C=CC(=O)N1CCc2nn(-c3ccc(C4CC4)cc3)c3c2C(C1)N(C(=O)c1ccn(CC(F)(F)F)c(=O)c1)CC3

InChI Key InChIKey=XVAJYXNTIJPKFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42423   

LigandChemical structure of BindingDB Monomer ID 42423BDBM42423(4-(7-acryloyl-2-(4- cyclopropylphenyl)- 3,4,5,5a,6...)
Affinity DataIC50: 55nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 42423BDBM42423(4-(7-acryloyl-2-(4- cyclopropylphenyl)- 3,4,5,5a,6...)
Affinity DataIC50: 55nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details
US Patent