BDBM43366 5'-isopropyl-5-phenyl-spiro[3H-1,3,4-thiadiazole-2,3'-indoline]-2'-one::5'-phenyl-5-propan-2-yl-2-spiro[1H-indole-3,2'-3H-1,3,4-thiadiazole]one::5'-phenyl-5-propan-2-yl-spiro[1H-indole-3,2'-3H-1,3,4-thiadiazole]-2-one::5'-phenyl-5-propan-2-ylspiro[1H-indole-3,2'-3H-1,3,4-thiadiazole]-2-one::MLS000528096::SMR000120670::cid_3154392

SMILES CC(C)c1ccc2NC(=O)C3(NN=C(S3)c3ccccc3)c2c1

InChI Key InChIKey=HAUQIWOBYGUGLK-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 43366   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43366(5'-isopropyl-5-phenyl-spiro[3H-1,3,4-thiadiazole-2...)
Affinity DataEC50:  1.42E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43366(5'-isopropyl-5-phenyl-spiro[3H-1,3,4-thiadiazole-2...)
Affinity DataEC50:  1.42E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43366(5'-isopropyl-5-phenyl-spiro[3H-1,3,4-thiadiazole-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mus musculus)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43366(5'-isopropyl-5-phenyl-spiro[3H-1,3,4-thiadiazole-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetX-box-binding protein 1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM43366(5'-isopropyl-5-phenyl-spiro[3H-1,3,4-thiadiazole-2...)
Affinity DataIC50:  500nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM43366(5'-isopropyl-5-phenyl-spiro[3H-1,3,4-thiadiazole-2...)
Affinity DataEC50:  430nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay