BDBM435334 US10568876, Example 96::methyl 3-(2-((1-cyclopropyl-2,5-dimethyl- 1H-pyrrol-3-yl)methyl)-8-((2- phenylcyclopropanecarboxamido)methyl)- 1,2,3,4-tetrahydroisoquinolin-5- yl)benzoate (mixture of 4 isomers)

SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccccc2)c2CN(Cc3cc(C)n(C4CC4)c3C)CCc12

InChI Key InChIKey=BQGTXXVCMUZQNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435334   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 435334BDBM435334(US10568876, Example 96 | methyl 3-(2-((1-cycloprop...)
Affinity DataIC50: 2.80E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent