BDBM438946 3-(tert-butyl)-1,5,3-dioxazepane::US10604489, Compound 107::US11180455, Compound 107

SMILES COC1(C2CCCC1CN(C2)C(C)(C)C)c1ccnc(c1)C(N)=O

InChI Key InChIKey=GYPDOIQHKDGWQE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438946   

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandChemical structure of BindingDB Monomer ID 438946BDBM438946(3-(tert-butyl)-1,5,3-dioxazepane | US10604489, Com...)
Affinity DataKi:  3nMAssay Description:Membrane protein from CHO (Chinese Hamster Ovarian) cells that stably expressed one type of the cloned human opioid receptor were incubated with 12 d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Alkermes

US Patent
LigandChemical structure of BindingDB Monomer ID 438946BDBM438946(3-(tert-butyl)-1,5,3-dioxazepane | US10604489, Com...)
Affinity DataKi:  3nMAssay Description:The Ki (binding affinity) for μ-receptor was determined with a previously described method using a competitive displacement assay (Neumeyer et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent