BDBM442766 1,6-Dimethyl-N- (1-{4- [(trifluoromethyl)- sulfanyl]phenyl}- cyclopropyl)-1H- pyrazolo[3,4-d]- pyrimidin-4-amine::US10647727, Example 23
SMILES Cc1nc(NC2(CC2)c2ccc(SC(F)(F)F)cc2)c2cnn(C)c2n1
InChI Key InChIKey=TZIIVJMNZFTMKG-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 442766
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 16nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair