BDBM445688 Ex. 24/KM-06-112/(I-24)::US10683309, Example 24::US11028104, Example 24
SMILES CCn1c2nc(Cc3cn4ccccc4n3)n(Cc3ccc(CC(O)=O)cc3)c2c(=O)[nH]c1=O
InChI Key InChIKey=FZYXGHVDIAXWRR-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 445688
Affinity DataIC50: 3.11E+3nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+3nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of recombinant MBP-tagged full length human THP2 using L-Trp as substrate assessed as formation of 5-HTP by measuring fluorescent propertyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+5nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+5nMAssay Description:The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...More data for this Ligand-Target Pair