BDBM450393 2-[6-(4- Acetylpiperazin-1- yl)-4- oxoquinazolin-3- yl]acetic acid (intermediate A-2) and (6- chloropyridin-3- yl)methanamine ([CAS RN 97004- 04-1])::US10676446, Example 11

SMILES CC(=O)N1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(Cl)nc3)c(=O)c2c1

InChI Key InChIKey=RRKWKDPBMXWOLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450393   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 450393BDBM450393(US10676446, Example 11 | 2-[6-(4- Acetylpiperazin-...)
Affinity DataIC50: 119nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
US Patent