BDBM456277 6-(4-(((1-hydroxy-1-(4- methyl-1-oxo-1,3- dihydroisobenzofuran-5- yl)propan-2- yl)amino)methyl)-1H- pyrazol-1-yl)-4- methylnicotinonitrile (Enantiomer-I)::US10723723, Example 176-I
SMILES CC(NCc1cnn(c1)-c1cc(C)c(cn1)C#N)C(O)c1ccc2C(=O)OCc2c1C
InChI Key InChIKey=MUQMFRIFLPZDLY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 456277
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 4nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair