BDBM463227 4-Amino-5-(4-hydroxyphenyl)-5- methyl-2-(8-(3,3,4,4,4- pentafluorobutyl)imidazo[1,2- a]pyrazin-6-yl)-5,7-dihydro-6H- pyrrolo[2,3-d]pyrimidin-6-one::US10780092, Example 81-B

SMILES CC1(C(=O)Nc2nc(nc(N)c12)-c1cn2ccnc2c(CCC(F)(F)C(F)(F)F)n1)c1ccc(Cl)cc1

InChI Key InChIKey=XUAHFEOHPUQMFY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463227   

TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM463227(4-Amino-5-(4-hydroxyphenyl)-5- methyl-2-(8-(3,3,4,...)
Affinity DataKi:  13.9nMAssay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent