BDBM465370 US10793567, Compound 4::US11225479, Compound 4

SMILES Cc1ncc(s1)-c1ccc(N)c(NC(=O)N2Cc3cn(C)nc3C2)n1

InChI Key InChIKey=YQPXTBYQPWQDNB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 465370   

TargetHistone deacetylase 2(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM465370(US10793567, Compound 4 | US11225479, Compound 4)
Affinity DataIC50: >1.50E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465370(US10793567, Compound 4 | US11225479, Compound 4)
Affinity DataIC50:  2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM465370(US10793567, Compound 4 | US11225479, Compound 4)
Affinity DataIC50:  2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465370(US10793567, Compound 4 | US11225479, Compound 4)
Affinity DataIC50: >1.50E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent