BDBM465381 US10793567, Compound 17::US11225479, Compound 17

SMILES CCc1ncc2CN(Cc2n1)C(=O)Nc1nc(ccc1N)-c1ccc(F)cc1

InChI Key InChIKey=MGAPERLZFHUEQS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 465381   

TargetHistone deacetylase 2(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM465381(US10793567, Compound 17 | US11225479, Compound 17)
Affinity DataIC50:  1.25E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465381(US10793567, Compound 17 | US11225479, Compound 17)
Affinity DataIC50:  300nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Rodin Therapeutics

US Patent
LigandPNGBDBM465381(US10793567, Compound 17 | US11225479, Compound 17)
Affinity DataIC50:  300nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM465381(US10793567, Compound 17 | US11225479, Compound 17)
Affinity DataIC50:  1.25E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent