BDBM465729 2-[3-(2-amino-9H-purin-6-yl)-2- (hydroxymethyl)phenyl]-6-cyclopropyl- 8-fluoroisoquinolin-1(2H)-one::US10793575, Example 4

SMILES Nc1nc(-c2cccc(-n3ccc4cc(C5CC5)cc(F)c4c3=O)c2CO)c2nc[nH]c2n1

InChI Key InChIKey=DXXBDYLADWNKHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465729   

TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 465729BDBM465729(US10793575, Example 4 | 2-[3-(2-amino-9H-purin-6-y...)
Affinity DataIC50: 10nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent