BDBM466542 US10800739, Compound (20)::US11420940, cpd (20)

SMILES NC(=O)c1cccc2CN(CCCN3CCCc4ccccc34)C(=O)c12

InChI Key InChIKey=BLEKTFVHUNKMKI-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 466542   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM466542(US10800739, Compound (20) | US11420940, cpd (20))
Affinity DataKd: <30nMAssay Description:Preferably, for the screening method above cited, both the PARP protein and the 5H-phenanthridin-6-one-derived probe of formula (IP) are pre-mixed, o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM466542(US10800739, Compound (20) | US11420940, cpd (20))
Affinity DataKd:  190nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM466542(US10800739, Compound (20) | US11420940, cpd (20))
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM466542(US10800739, Compound (20) | US11420940, cpd (20))
Affinity DataKd:  190nMAssay Description:Preferably, for the screening method above cited, both the PARP protein and the 5H-phenanthridin-6-one-derived probe of formula (IP) are pre-mixed, o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent