BDBM466567 US10800755, Example 21::US11014905, Example 21
SMILES FC(F)(F)c1cccc(n1)C1CCN(CCNC(=O)[C@H]2C[C@@H]3CC[C@H]2O3)CC1
InChI Key InChIKey=LGQIOUYNFUYGTH-YQQAZPJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 466567
Affinity DataKi: 15nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataKi: 201nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataKi: 2.17E+3nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sumitomo Dainippon Pharma
US Patent
Sumitomo Dainippon Pharma
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The activity of the present compound for inhibiting hERG channel was measured by whole-cell patch clamp method with auto patch clamp system, using CH...More data for this Ligand-Target Pair
Affinity DataEC50: 65nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+3nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Affinity DataEC50: 84nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair