BDBM466882 US10800767, Example 26::US10800767, Example 27

SMILES CC(C)c1cc(Oc2c(Cl)cc(NC(=O)c3noc(=O)[nH]3)c(F)c2Cl)nn(C)c1=O

InChI Key InChIKey=KHCXAEVTULVXLE-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 466882   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466882(US10800767, Example 26 | US10800767, Example 27)
Affinity DataEC50:  58.1nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466882(US10800767, Example 26 | US10800767, Example 27)
Affinity DataEC50:  144nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466882(US10800767, Example 26 | US10800767, Example 27)
Affinity DataEC50:  26.8nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Terns

US Patent
LigandPNGBDBM466882(US10800767, Example 26 | US10800767, Example 27)
Affinity DataEC50:  699nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen™ TR-FRET Thyroid Receptor beta Coactivator Assay ki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent