BDBM467236 7-amino-3-(1-(but-2-ynoyl)pyrrolidin-3-yl)-1-(4-phenoxyphenyl)-1,5-dihydro-4H-pyrrolo[2,3-d]pyridazin-4-one ::US10800785, Example 2

SMILES CC#CC(=O)N1CCC(C1)c1cn(-c2ccc(Oc3ccccc3)cc2)c2c(N)n[nH]c(=O)c12

InChI Key InChIKey=PHISSYWFXLOCLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 467236   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467236(7-amino-3-(1-(but-2-ynoyl)pyrrolidin-3-yl)-1-(4-ph...)
Affinity DataIC50:  244nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM467236(7-amino-3-(1-(but-2-ynoyl)pyrrolidin-3-yl)-1-(4-ph...)
Affinity DataIC50:  244nMAssay Description:MTS testing kit was purchased from Promega. The DMEM, Fetal bovine serum and Penicillin-Streptomycin were purchased from Gibco. Dimethyl sulfoxide (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent