BDBM468304 US10806720, Compound 100::US11230523, Compound 100::US11648234, Compound 100

SMILES C[C@](O)(CN1CCc2cc(Br)ccc12)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=CEYWGAYFMHMNAF-IBGZPJMESA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 468304   

TargetAndrogen receptor(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468304(US10806720, Compound 100 | US11230523, Compound 10...)
Affinity DataKi:  198nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468304(US10806720, Compound 100 | US11230523, Compound 10...)
Affinity DataKi:  198nMAssay Description:hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD was combin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468304(US10806720, Compound 100 | US11230523, Compound 10...)
Affinity DataKi:  198nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468304(US10806720, Compound 100 | US11230523, Compound 10...)
Affinity DataIC50:  531nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM468304(US10806720, Compound 100 | US11230523, Compound 10...)
Affinity DataIC50:  531nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent