BDBM469086 2-methyl-4-[2-methyl-1,1-dioxo-5-(2,2,2- trifluoroethoxy)-3H-1,2-benzothiazol-6- yl]isoquinolin-1-one::US10807982, Example 10
SMILES CN1Cc2cc(OCC(F)(F)F)c(cc2S1(=O)=O)-c1cn(C)c(=O)c2ccccc12
InChI Key InChIKey=YDFUVNCBHJXIGC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 469086
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair