BDBM469106 US10807974, Example 125::US10995088, Example 125::US11608330, Example 125

SMILES CN(C)C(=O)c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1

InChI Key InChIKey=DLDHQUYJALROQX-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 469106   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50:  180nMAssay Description:LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 1 hour at room temp on a plate shaker.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402, MAO-A Enzyme: Promega, Cat No. V1452.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402, MAO-B Enzyme: Sigma, Cat No. M7441.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Promega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50:  180nMAssay Description:10. Incubate for 1 hr at room temp on a plate shaker, protected from light.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The following reagents were prepared:ReagentsMAO-Glo Assay Kit: Promega, Cat No. V1402MAO-B Enzyme: Sigma, Cat No. M7441Deprenyl: Sigma, Cat No. M003...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:ReagentsPromega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821Inhibitors (Test Compounds):10 mM stock diluted to 10, 3, 1, 0.3, 0.1, 0.03, 0.01, 0.003,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50:  180nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-B Enzyme: Sigma, Cat No. M7441Deprenyl: Sigma, Cat No. M003Assay Plates: 96 well white polystyrene, flat bottom plates, no lid: Fisher, Cat No. D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Promega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821Inhibitors (Test compounds):10 mM stock diluted to 10, 3, 1, 0.3, 0.1, 0.03, 0.01, 0.003, 0.001, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469106(US10807974, Example 125 | US10995088, Example 125 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The following reagents were prepared:ReagentsMAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent