BDBM469157 N-[6-(1,5-dimethyl-6-oxopyridin-3-yl)-1-[(4- fluorophenyl)methyl]-2-methylbenzimidazol-4- yl]methanesulfonamide::US10807982, Example 37

SMILES Cc1nc2c(NS(C)(=O)=O)cc(cc2n1Cc1ccc(F)cc1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=KUEYACBOLWXVBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469157   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469157(N-[6-(1,5-dimethyl-6-oxopyridin-3-yl)-1-[(4- fluor...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent