BDBM469189 5-[3-(cyclopropylmethyl)-7-ethylsulfonyl-2- methylbenzimidazol-5-yl]-1,3- dimethylpyridin-2-one::US10807982, Example 69

SMILES CCS(=O)(=O)c1cc(cc2n(CC3CC3)c(C)nc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=PPLIPROVDQHRNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469189   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469189(5-[3-(cyclopropylmethyl)-7-ethylsulfonyl-2- methyl...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent