BDBM469207 N-[4-(2,4-difluorophenoxy)-3-(2,2,6-trimethyl-5- oxo-1,3-dihydroindolizin-8- yl)phenyl]methanesulfonamide::US10807982, Example 88

SMILES Cc1cc(c2CC(C)(C)Cn2c1=O)-c1cc(NS(C)(=O)=O)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=GROYKANRBMYEOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469207   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469207(N-[4-(2,4-difluorophenoxy)-3-(2,2,6-trimethyl-5- o...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent