BDBM469221 N-[5-(1,5-dimethyl-6-oxopyridin-3-yl)-3-[(4- fluorophenyl)methyl]-2-oxo-1,3-benzoxazol-7- yl]methanesulfonamide::US10807982, Example 102

SMILES Cc1cc(cn(C)c1=O)-c1cc(NS(C)(=O)=O)c2oc(=O)n(Cc3ccc(F)cc3)c2c1

InChI Key InChIKey=OBWZHFLXXDRKPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469221   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM469221(N-[5-(1,5-dimethyl-6-oxopyridin-3-yl)-3-[(4- fluor...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent