BDBM470132 US10807994, Compound 1.8::US10807994, Example S-8

SMILES OCC(=O)N1CCN(CC1)c1ccc(Nc2ncc3C(=O)N(COc3n2)c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=OTTLNVOXJYLFDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470132   

TargetWee1-like protein kinase(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM470132(US10807994, Compound 1.8 | US10807994, Example S-8)
Affinity DataIC50:  162nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen™ Terbium Labeled TR-FRET assay. Kinase assays were performed in 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent