BDBM470287 N-[3-(7-{1-[2-(3,3-Difluoropyrrolidin-1-yl)-1-methyl-2-oxoethyl]-1H-pyrazol-4-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea::US10813930, Ex. No. 65

SMILES CC(C(=O)N1CCC(F)(F)C1)n1cc(cn1)-c1cnn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1

InChI Key InChIKey=UXDIXKYFTGYARJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470287   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 470287BDBM470287(US10813930, Ex. No. 65 | N-[3-(7-{1-[2-(3,3-Difluo...)
Affinity DataIC50: 10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
US Patent