BDBM471515 US10821115, Example 100532::US11224601, Example 100532
SMILES C[C@H]1C\C=C\[C@](O)(Cc2cc(C)ccn2)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)C(=O)NS(=O)(=O)[C@@H]1C
InChI Key InChIKey=DQOIRRCXKCBORB-XWTXNUCNSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 471515
TargetBcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 0.0530nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 0.0530nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair